Which breed originates from hybridization of Donkey and Horse?

The breed that originates from the hybridization of a donkey and a horse is indeed a mule. Mules are the offspring of a male donkey (called a jack) and a female horse (called a mare). This hybridization results in a creature that inherits characteristics from both parents, often possessing the strength and endurance of a donkey while also gaining some of the desirable traits of a horse, such as size and temperament.

Mules are valued for their hardiness, intelligence, and adaptability, which are essential traits for work animals. Unlike purebred horses or donkeys, mules are often more resilient to certain health issues and can thrive in challenging environments. Their unique genetic makeup also means they are typically sterile, which is a common characteristic of many hybrids, limiting their ability to reproduce.

The other choices listed, such as the Cream Draft Horse, American Saddlebred, and Tennessee Walking Horse, are all distinct horse breeds that have their own specific lineage and characteristics, entirely separate from mules and their donkey-horse hybridization.